Methyl 3-Aminothiopheno[2,3-B]Pyridine-2-Carboxylate

Methyl 3-Aminothiopheno[2,3-B]Pyridine-2-Carboxylate - Names and Identifiers

Name	Methyl 3-Aminothieno[2,3-B]Pyridine-2-Carboxylate
Synonyms	AKOS 93608 3-AMino-2-carboMethoxythieno[2,3-b]pyridine 2-(Methoxycarbonyl)thieno[2,3-b]pyridin-3-amine METHYL 3-AMINOTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE Methyl 3-Aminothieno[2,3-B]Pyridine-2-Carboxylate METHYL 3-AMINOTHIOPHENO[2,3-B]PYRIDINE-2-CARBOXYLATE Methyl 3-Aminothiopheno[2,3-B]Pyridine-2-Carboxylate 3-AMino-thieno[2,3-b]pyridin-2-carboxylic acid Methyl ester Thieno[2,3-B]Pyridine-2-Carboxylic Acid, 3-Amino-, Methyl Ester Thieno[2,3-b]pyridine-2-carboxylic acid, 3-amino-, methyl ester (9CI) 3-Amino-2-(methoxycarbonyl)-7-azabenzo[b]thiophene, 3-Amino-2-(methoxycarbonyl)thieno[2,3-b]pyridine
CAS	111042-89-8
InChI	InChI=1/C9H8N2O2S/c1-13-9(12)7-6(10)5-3-2-4-11-8(5)14-7/h2-4H,10H2,1H3

Methyl 3-Aminothiopheno[2,3-B]Pyridine-2-Carboxylate - Physico-chemical Properties

Molecular Formula	C9H8N2O2S
Molar Mass	208.24
Density	1.422±0.06 g/cm3(Predicted)
Melting Point	198-200°C
Boling Point	377.6±37.0 °C(Predicted)
Flash Point	182.1°C
Vapor Presure	6.69E-06mmHg at 25°C
pKa	4.96±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.699

Methyl 3-Aminothiopheno[2,3-B]Pyridine-2-Carboxylate - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

Methyl 3-Aminothiopheno[2,3-B]Pyridine-2-Carboxylate - Introduction

Methyl 3-aminopyridylthiophene-2-carboxylate is an organic compound with the chemical formula C10H10N2SO2; it is an organic acid methyl ester with aromatic properties.

The main properties of 3-aminopyridine thiophene-2-carboxylic acid methyl ester include:
1. Appearance and state: colorless to light yellow crystal;
2. melting point: about 120-124 degrees Celsius;
3. solubility: soluble in some organic solvents such as toluene and dichloromethane, insoluble in water.

3-aminopyridine thiophene-2-carboxylic acid methyl ester has certain application value in the field of medicine:
1. It can be used as a synthetic intermediate for drug synthesis in the pharmaceutical field;
2. As an organic synthesis reagent, a catalyst for organic chemical reactions.

The preparation method of 3-aminopyridine thiophene-2-carboxylic acid methyl ester can be carried out by the following steps:
1. dissolving 3-aminopyridine thiophene-2-acid in an appropriate amount of organic solvent;
2. Add an appropriate amount of methanol to it;
3. carry out esterification reaction under appropriate reaction conditions;
4. The precipitate was filtered and the product was washed and dried.

Regarding safety information, 3-aminopyridine thiophene-2-carboxylic acid methyl ester may corrode in humid environments. During use, contact with skin, eyes and respiratory tract should be avoided. Protective gloves, goggles and masks must be worn during operation. Operate in a well-ventilated area and away from fire and high temperature conditions. In case of contact, flush immediately with plenty of water and seek medical attention.

Last Update：2024-04-09 20:02:46